IndiumV2, Main, Exploration, bibRecord, 000620

In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles.

Identifieur interne : 000620 ( Main/Exploration ); précédent : 000619; suivant : 000621

In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles.

Auteurs : RBID : pubmed:23467614

English descriptors

KwdEn :
- Animals, Contrast Media (chemistry), Contrast Media (diagnostic use), Contrast Media (therapeutic use), Gadolinium (chemistry), Heterocyclic Compounds, 1-Ring (chemistry), Indium Radioisotopes (chemistry), Isotope Labeling, Knee Joint (radionuclide imaging), Nanoparticles (chemistry), Nanoparticles (diagnostic use), Nanoparticles (therapeutic use), Neoplasms (drug therapy), Neoplasms (radionuclide imaging), Proteoglycans (chemistry), Proteoglycans (metabolism), Pyridinium Compounds (chemistry), Quantum Dots, Quaternary Ammonium Compounds (chemistry), Rats.
MESH :
- chemical , chemistry : Contrast Media, Gadolinium, Heterocyclic Compounds, 1-Ring, Indium Radioisotopes, Proteoglycans, Pyridinium Compounds, Quaternary Ammonium Compounds.
- chemical , diagnostic use : Contrast Media.
- chemical , metabolism : Proteoglycans.
- chemical , therapeutic use : Contrast Media.
- chemistry : Nanoparticles.
- diagnostic use : Nanoparticles.
- drug therapy : Neoplasms.
- radionuclide imaging : Knee Joint, Neoplasms.
- therapeutic use : Nanoparticles.
- Animals, Isotope Labeling, Quantum Dots, Rats.

Abstract

Ultrasmall gadolinium based particles have been functionalized with positively charged pyridinium quaternary ammonium and labelled with (111)In. Evidence of their active targeting properties towards proteoglycans has been demonstrated in vivo after intravenous injection into rats opening thus a route to cancer imaging and therapy.

DOI: 10.1039/c3cc39106j
PubMed: 23467614

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000757
to stream Main, to step Curation: 000757

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles.</title>
<author><name sortKey="Morlieras, Jessica" uniqKey="Morlieras J">Jessica Morlieras</name>
<affiliation wicri:level="3"><nlm:affiliation>Laboratoire de Physico-Chimie des Matériaux Luminescents, UMR 5620 CNRS - Université Claude Bernard Lyon 1, Université de Lyon, 69622 Villeurbanne Cedex, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Laboratoire de Physico-Chimie des Matériaux Luminescents, UMR 5620 CNRS - Université Claude Bernard Lyon 1, Université de Lyon, 69622 Villeurbanne Cedex</wicri:regionArea>
<placeName><region type="region" nuts="2">Rhône-Alpes</region>
<settlement type="city">Villeurbanne</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chezal, Jean Michel" uniqKey="Chezal J">Jean-Michel Chezal</name>
</author>
<author><name sortKey="Miot Noirault, Elizabeth" uniqKey="Miot Noirault E">Elizabeth Miot-Noirault</name>
</author>
<author><name sortKey="Vidal, Aurelien" uniqKey="Vidal A">Aurélien Vidal</name>
</author>
<author><name sortKey="Besse, Sophie" uniqKey="Besse S">Sophie Besse</name>
</author>
<author><name sortKey="Kryza, David" uniqKey="Kryza D">David Kryza</name>
</author>
<author><name sortKey="Truillet, Charles" uniqKey="Truillet C">Charles Truillet</name>
</author>
<author><name sortKey="Mignot, Anna" uniqKey="Mignot A">Anna Mignot</name>
</author>
<author><name sortKey="Antoine, Rodolphe" uniqKey="Antoine R">Rodolphe Antoine</name>
</author>
<author><name sortKey="Dugourd, Philippe" uniqKey="Dugourd P">Philippe Dugourd</name>
</author>
<author><name sortKey="Redini, Francoise" uniqKey="Redini F">Françoise Redini</name>
</author>
<author><name sortKey="Sancey, Lucie" uniqKey="Sancey L">Lucie Sancey</name>
</author>
<author><name sortKey="Lux, Francois" uniqKey="Lux F">François Lux</name>
</author>
<author><name sortKey="Perriat, Pascal" uniqKey="Perriat P">Pascal Perriat</name>
</author>
<author><name sortKey="Janier, Marc" uniqKey="Janier M">Marc Janier</name>
</author>
<author><name sortKey="Tillement, Olivier" uniqKey="Tillement O">Olivier Tillement</name>
</author>
</titleStmt>
<publicationStmt><date when="2013">2013</date>
<idno type="doi">10.1039/c3cc39106j</idno>
<idno type="RBID">pubmed:23467614</idno>
<idno type="pmid">23467614</idno>
<idno type="wicri:Area/Main/Corpus">000757</idno>
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</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Contrast Media (chemistry)</term>
<term>Contrast Media (diagnostic use)</term>
<term>Contrast Media (therapeutic use)</term>
<term>Gadolinium (chemistry)</term>
<term>Heterocyclic Compounds, 1-Ring (chemistry)</term>
<term>Indium Radioisotopes (chemistry)</term>
<term>Isotope Labeling</term>
<term>Knee Joint (radionuclide imaging)</term>
<term>Nanoparticles (chemistry)</term>
<term>Nanoparticles (diagnostic use)</term>
<term>Nanoparticles (therapeutic use)</term>
<term>Neoplasms (drug therapy)</term>
<term>Neoplasms (radionuclide imaging)</term>
<term>Proteoglycans (chemistry)</term>
<term>Proteoglycans (metabolism)</term>
<term>Pyridinium Compounds (chemistry)</term>
<term>Quantum Dots</term>
<term>Quaternary Ammonium Compounds (chemistry)</term>
<term>Rats</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Contrast Media</term>
<term>Gadolinium</term>
<term>Heterocyclic Compounds, 1-Ring</term>
<term>Indium Radioisotopes</term>
<term>Proteoglycans</term>
<term>Pyridinium Compounds</term>
<term>Quaternary Ammonium Compounds</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Contrast Media</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Proteoglycans</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Contrast Media</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Nanoparticles</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic use" xml:lang="en"><term>Nanoparticles</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Knee Joint</term>
<term>Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="therapeutic use" xml:lang="en"><term>Nanoparticles</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Isotope Labeling</term>
<term>Quantum Dots</term>
<term>Rats</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Ultrasmall gadolinium based particles have been functionalized with positively charged pyridinium quaternary ammonium and labelled with (111)In. Evidence of their active targeting properties towards proteoglycans has been demonstrated in vivo after intravenous injection into rats opening thus a route to cancer imaging and therapy.</div>
</front>
</TEI>
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<DateCreated><Year>2013</Year>
<Month>03</Month>
<Day>15</Day>
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<DateCompleted><Year>2013</Year>
<Month>09</Month>
<Day>09</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1364-548X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>49</Volume>
<Issue>29</Issue>
<PubDate><Year>2013</Year>
<Month>Apr</Month>
<Day>14</Day>
</PubDate>
</JournalIssue>
<Title>Chemical communications (Cambridge, England)</Title>
<ISOAbbreviation>Chem. Commun. (Camb.)</ISOAbbreviation>
</Journal>
<ArticleTitle>In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles.</ArticleTitle>
<Pagination><MedlinePgn>3046-8</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1039/c3cc39106j</ELocationID>
<Abstract><AbstractText>Ultrasmall gadolinium based particles have been functionalized with positively charged pyridinium quaternary ammonium and labelled with (111)In. Evidence of their active targeting properties towards proteoglycans has been demonstrated in vivo after intravenous injection into rats opening thus a route to cancer imaging and therapy.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Morlieras</LastName>
<ForeName>Jessica</ForeName>
<Initials>J</Initials>
<Affiliation>Laboratoire de Physico-Chimie des Matériaux Luminescents, UMR 5620 CNRS - Université Claude Bernard Lyon 1, Université de Lyon, 69622 Villeurbanne Cedex, France.</Affiliation>
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<Author ValidYN="Y"><LastName>Chezal</LastName>
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<Author ValidYN="Y"><LastName>Miot-Noirault</LastName>
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<Author ValidYN="Y"><LastName>Vidal</LastName>
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<Author ValidYN="Y"><LastName>Besse</LastName>
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<Author ValidYN="Y"><LastName>Kryza</LastName>
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<Author ValidYN="Y"><LastName>Truillet</LastName>
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<Author ValidYN="Y"><LastName>Mignot</LastName>
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<Author ValidYN="Y"><LastName>Antoine</LastName>
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<Author ValidYN="Y"><LastName>Sancey</LastName>
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<Author ValidYN="Y"><LastName>Perriat</LastName>
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<Author ValidYN="Y"><LastName>Janier</LastName>
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<Language>eng</Language>
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<PublicationType>Research Support, Non-U.S. Gov't</PublicationType>
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<MedlineTA>Chem Commun (Camb)</MedlineTA>
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<ISSNLinking>1359-7345</ISSNLinking>
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<QualifierName MajorTopicYN="Y">chemistry</QualifierName>
<QualifierName MajorTopicYN="N">diagnostic use</QualifierName>
<QualifierName MajorTopicYN="N">therapeutic use</QualifierName>
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<QualifierName MajorTopicYN="Y">chemistry</QualifierName>
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<QualifierName MajorTopicYN="N">therapeutic use</QualifierName>
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<QualifierName MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName MajorTopicYN="N">radionuclide imaging</QualifierName>
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<MeshHeading><DescriptorName MajorTopicYN="N">Proteoglycans</DescriptorName>
<QualifierName MajorTopicYN="N">chemistry</QualifierName>
<QualifierName MajorTopicYN="N">metabolism</QualifierName>
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<MeshHeading><DescriptorName MajorTopicYN="N">Pyridinium Compounds</DescriptorName>
<QualifierName MajorTopicYN="Y">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Quantum Dots</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Quaternary Ammonium Compounds</DescriptorName>
<QualifierName MajorTopicYN="N">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Rats</DescriptorName>
</MeshHeading>
</MeshHeadingList>
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In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles.

In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles.

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki